Sicily, the largest island in the Mediterranean, offers a great mix of ancient history, magical landscapes, and fascinating culture. If you’re planning your trip, this 10-day Sicily itinerary will help you make the most of your first visit. Choose between two routes: one focusing on the north and northwest, and the other on the east and southeast.
Read also: 6 Most Touristy Places in Sicily and Where To Go Instead
Quick Sicily Travel Guide
Sicily Accommodation: San Domenico Palace and Grand Hotel Timeo for luxury accommodation in Taormina, and Casa Nostra Boutique Hotel or Palazzo Natoli Boutique Hotel for intimate vibes in Palermo. Dome or B&B Oriental Palace in Catania. Room Of Andrea Hotel or Gaura Apartments in Trapani. Le Tre Campane Ortigia or Palazzo Alfeo Aparthotel in Syracuse. Principe Di Salina Boutique Hotel or Il Gabbiano Relais in Stromboli on the Aeolian Islands.
Top Sicily Activities:
- Palermo street food walking tour
- Etna, wine and Alcantara tour from Taormina
- Boat tour to Favignana and Levanzo from Trapani
- Private tour of 3 Etna wineries with food and wine tasting
- Travel photoshoot in Palermo
- Quad excursion from Ribera
Option 1: 10 days exploring northern and northwestern Sicily
Day 1-2: Palermo – The heart of Sicily’s culture

Start your journey in Palermo, Sicily’s amazing capital. Explore the Palermo Cathedral, the Norman Palace, and the Palatine Chapel, a UNESCO World Heritage Site. Wander through the Ballarò and Vucciria markets to experience the city’s street food scene. Don’t miss a taste of panelle (chickpea fritters) and arancine.
In the late afternoon, walk along the Foro Italico, La Cala and Molo Trapezioidale promenades and enjoy a dinner of fresh seafood in the historic La Kalsa district.
Check out our guide to the best hotels in Palermo, featuring top picks for every traveler seeking comfort and charm. Traveling on a budget? Don’t worry—we’ve curated another guide with the best affordable accommodations to help you save while enjoying the beauty of Sicily.
Day 3: Monreale and Cefalù

Spend the morning visiting Monreale’s magnificent cathedral, famous for its golden mosaics. Afterward, head to the coastal town of Cefalù, known for its picturesque medieval streets, sandy beach, and the impressive Cathedral of Cefalù. Climb La Rocca for panoramic views of the town and sea.
If you’re planning to stay in Cefalù, we’ve got the perfect guide for you! Click here to discover the best places to stay in Cefalù.
Day 4-5: Trapani and Erice

Drive to Trapani and take a day trip to the hilltop town of Erice, a medieval gem with cobbled streets and breathtaking views. Visit the Venus Castle and sample the local almond pastries.
On the second day, explore Trapani’s salt pans and windmills or as an extra idea, take a ferry to the Egadi Islands for swimming, hiking and snorkeling. For an unforgettable experience, check out the One Day Boat Tour in the Egadi Islands: Favignana and Levanzo departing from Trapani. It’s the perfect way to explore these stunning islands!
Day 6-7: San Vito Lo Capo and Zingaro Nature Reserve

Head to San Vito Lo Capo, a beach paradise with turquoise waters and soft sand. Spend a day relaxing or trying couscous, the town’s culinary specialty.
The next day, hike through the Zingaro Nature Reserve, a stunning coastal park with secluded coves and pristine waters perfect for swimming.
Day 8-10: Segesta, Selinunte, and Marsala

Visit the ancient Greek temples at Segesta or Selinunte to marvel at Sicily’s archaeological wonders. End your trip in Marsala, famous for its fortified wine. Enjoy a sunset wine tasting in the salt pans of Marsala or take a boat ride to the Stagnone Lagoon.
Option 2: 10 days exploring eastern and southeastern Sicily
Day 1-2: Catania and Mount Etna

Begin in Catania, a city known for its baroque architecture and vibrant energy. Visit Piazza Duomo, the Cathedral of Saint Agatha, and the bustling La Pescheria fish market. Try the local specialties like pasta alla Norma and cannoli.
Take a day trip to Mount Etna, Europe’s highest active volcano, for a guided hike or a cable car ride to the summit. Don’t miss the Etna, Wine, and Alcantara Tour for an incredible adventure combining Sicily’s natural beauty and flavors!
Day 3-4: Taormina and Isola Bella

Travel to Taormina, Sicily’s chic resort town. Explore the Greek Theatre with its spectacular views of Mount Etna and the Ionian Sea. Wander through the town’s historic streets, and relax on the beaches near Isola Bella, a picturesque nature reserve.
Day 5: Syracuse and it’s historic center Ortigia

Head south to Syracuse, once one of the most powerful cities of the ancient world. Visit the Neapolis Archaeological Park, home to the Greek Theatre and Ear of Dionysius. Spend the evening exploring Ortigia, Syracuse’s historic island district, with its baroque Piazza Duomo and waterfront restaurants.
Day 6-8: Ragusa, Modica, and Scicli

Discover the baroque beauty of Ragusa Ibla, Modica, and Scicli, part of the UNESCO-listed Val di Noto. Admire the stunning architecture, sample Modica’s famous chocolate, and enjoy the slower pace of these charming towns.
Day 9-10: Noto and Vendicari Nature Reserve

Conclude your trip in Noto, renowned for its baroque cathedral and palaces. Spend your final day at the Vendicari Nature Reserve, a relaxing coastal park with sandy beaches, walking trails, and flamingos.
For a memorable send-off, have a Sicilian feast featuring seafood and local wines.
Tips for Planning Your Sicily Trip
- When to visit: Spring (April-May) and autumn (September-October) offer pleasant weather and fewer crowds.
- Getting around: Renting a car is essential for exploring Sicily’s diverse landscapes and hidden gems.
- Don’t miss: Sampling Sicilian wine, granita, cannoli and authentic gelato in every town you visit.
Both parts of Sicily are absolute must-sees, each offering unique experiences and breathtaking things to see. We recommend focusing on just one area during your trip to avoid feeling rushed. Even with this approach, your days will be filled with incredible activities and many magical moments. Have a beautiful trip and enjoy every second of your Sicilian adventure!
All the photos featured in this article were captured by Chiara Magi. Book your travel photoshoot in Palermo here or write us at [email protected].
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